Longevity Research
Thinkers posting on this topic
No compiled wiki article for this topic yet. Raw entries below are the source material — a wiki article can be generated on demand from /admin/triggers.
All entries on this topic (2)
Harvard's Sinclair: Aging Reversible via Epigenetic Reset, Human Trials Imminent
Dr. David Sinclair's information theory posits aging as epigenetic information loss causing cellular identity crises, reversible by reinstalling youthful epigenetic patterns using three genes (OSK factors) that reset tissue age by ~75% without full dedifferentiation. Lab results show whole-body reju…
Yamanaka Factors Enable Epigenetic Rejuvenation for Age Reversal
Aging arises from epigenetic drift where DNA repair misplaces gene switches, causing cellular dysfunction across tissues. Yamanaka factors, four proteins discovered in 2006, fully reprogram cells to pluripotent stem cells; partial application resets epigenomes to youthful states without dedifferenti…